@TOME V2.2
(Nov 2016)
Ref.
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : T0771: (2014-05-09 )
MKRLLLITLLIGYIYPCVAQDKPIRTEESLEGTVIYKKTTTFEVDGYTYQCDVDDGSQFVTLYNKENKLTYEKIVYKDTGKTYIGSWSSNVIEYDRFMSQQADFIVDQAFTKAMADEIGKTELMITMLLSPNTGEVMEVNFNFFTFEPYAKVPLHVYREIEVKLKEQIHFKPIEEGKQLNYIMLAWMQKPQGKLPPLPPPGSLM
Atome Classification :
(20 SA)
------------------.........10-...----...------...20........30-........40.....--...50........60......-..70......-----.--.80-....----...-.90....--..-..100.......110......-------------.120...---------....130.......-140.-......150.----......160---...-.-------------------------------....170...-----------....------180....--------.--..190...-.----------...200..-------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
------------------MKR
L
L
L
I
T
L
L
--
I
G
Y
----
I
Y
P
------CVAQDKPIRTEESLE-
G
T
V
I
Y
K
K
T
T
T
F
E
VD
G
--
Y
T
Y
Q
C
DVDDG
S
Q
F
V
T
L
YNKEN-KL
T
Y
E
K
I
V
Y
K-----D--TG
K
-
T
Y
IG----SWS-S
N
V
I
E
Y
D
--
R
F
-
M
S
Q
Q
A
D
F
I
V
D
Q
A
F
T
K
A
M
A
D
EI-------------GK
T
E
L
M
I
---------
T
M
L
LSPNTG
E
V
M
E
V
-
N
F
N
F
-
F
T
FEPYAKV
P
----
L
H
V
Y
R
E
I
E
----
V
K
L
-
K
-------------------------------EQIH
F
K
PIEE-----------GKQL------
N
Y
I
M
L
A
W
--------M--QKPQGKLP-P----------LPPPGSLM-------------------------------------------------
26
Fugue
85.70
11%
-44
- C5 -
2J0A
-
MFNG_MOUSE
A:
[9-277]
ELQLGD
I
F
I
A
V
K
T
T
WAFH
R
S
R
L
D
L
L
L
D
T
--
W
V
S
RIRQ
Q
T
F
------
I
F
T
D
S
P
D
E
R
L
Q
E
R
L
G
-
P
H
L
V
V
T
Q
C
A
L
S
C
K
M
A
--
A
E
F
D
A
F
L
V
S
G
L
R
W
F
C
H
V
D
D
D
N
-
Y
V
N
P
K
A
L
L
Q
L
L
K
T
FP
Q
--
D
R
D
-
V
Y
V
G
----
K
P
S
-
L
F
-------
W
F
-
A
T
G
G
A
G
F
C
I
N
R
Q
L
A
L
K
M
V
P
W
A
SGSHFVDT
S
A
L
I
R
L
P
D
D
C
T
V
---------
G
Y
I
I
E
C
K
L
G
G
R
L
Q
P
-
S
P
L
F
-
H
S
H
L
E
----
T
----
L
Q
L
L
G
A
A
Q
----
L
P
E
-
Q
-------------------------------
V
T
L
S
Y
G
V
F
E
G
-----------
K
L
N
V
------
I
K
L
P
G
P
F
SHEEDPSR
F
--
R
S
L
H
C
L
L
Y
-
P
----------
D
T
P
W
C
P
L
L
-------------------------------------------------
42
SP3
79.21
12%
-111
- C6 -
2HFT
-
?
?:
[107-218]
----------------------------------------------------------
N
L
--
G
Q
P
---
T
I
Q
S
F
E
Q
V
G
--
T
K
V
N
V
T
V
E
D
-------------
E
R
T
---
L
V
R
R
-----
N
------------------------
N
--
T
F
-
L
S
--------------
L
R
D
V
F
-------------
G
K
-
D
L
I
Y
---------
T
L
Y
Y
W
K
S
S
G
K
K
T
A
K
T
N
T
N
E
-
F
L
I
D
-----------------------------------------------------------------
V
D
K
-----------
G
E
N
Y
------
C
F
S
V
Q
A
V
--------
I
PS
R
T
V
N
R
K
S
T
-------------
D
S
P
V
E
C
M
G------------------------------------------------
30
Fugue
68.20
13%
-4
- C2 -
1R77
-
ALE1_STACP
A:
[264-362]
------------------------------------------------
D
D
D
K
V
K
L
Y
K
T
N
K
Y
-
G
T
L
Y
K
S
E
S
A
S
F
T
A
N
T
D
I
I
T
R
L
T
G
P
F
R
S
M
P
Q
S
G
V
L
R
K
G
L
-
T
I
K
Y
D
E
V
M
K
Q
-----
D
---
G
H
-
V
W
V
G
----
Y
N
T
-
N
S
--------
G
-
K
R
V
Y
L
P
V
R
T
W
N
E
S
T
G
E
L
G
P
L
W
-------------
G
T
I
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
62.64
28%
13
- C3 -
3F81
1
DUS3_HUMAN
A:
[53-113]
----------------------------------------------------------------------------
G
--
I
T
H
V
L
N
A
A
E
G
R
S
F
M
H
V
N
T
N
A
N
--------
F
Y
K
-----
D
--
S
G
I
-
T
Y
L
G
----
I
K
A
-
N
D
T
Q
E
F
N
LS
A
Y
-
F
E
R
A
A
D
F
I
-
D
Q
A
L
A
Q
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
34
Fugue
61.92
11%
-27
- C4 -
1LL3
2
GLYG_RABIT
A:
[1-266]
------------------
M
T
D
Q
A
F
V
T
L
T
TN
D
A
Y
----
A
K
G
------
A
L
V
L
G
S
S
L
K
Q
H
R
T
S
R
-
R
L
A
V
L
T
-
T
P
Q
V
S
D
T
M
--
R
K
A
L
E
I
V
F
D
E
V
I
T
V
D
I
L
D
S
G
D
-
S
A
H
L
T
L
M
K
R
P
-----
E
--
L
G
V
-
T
L
T
K
----
L
H
C
-
W
S
L
T
Q
Y
S
--
K
C
-
V
F
M
D
A
D
T
L
V
L
A
N
I
D
D
L
F
E
R
E
------------------------------
E
L
S
A
A
P
D
P
G
W
P
D
C
F
-
N
S
G
V
-
F
V
Y
Q
P
S
V
E
T
Y
----
N
Q
L
L
H
V
A
S
E
QGS
F
D
G
-
G
-------------------------------
D
Q
G
L
L
N
T
F
F
N
SWATTDIRKHL
P
F
I
Y
------
N
L
S
S
I
S
I
--------
Y
--
S
Y
L
P
A
F
K
A
-
F
----------
G
A
N
A
K
V
V
H
F
L
G
QTKPWN
Y
T
Y
D
TKTKSVRSEMTH
P
Q
F
L
N
V
W
W
D
I
F
T
T
S
V
V
P
L
L
Q
Q
F
G
L
2
PsiBlast_PDB
60.82
28%
17
- C3 -
1VHR
1
DUS3_HUMAN
A:
[54-114]
----------------------------------------------------------------------------
G
--
I
T
H
V
L
N
A
A
E
G
R
S
F
M
H
V
N
T
N
A
N
--------
F
Y
K
-----
D
--
S
G
I
-
T
Y
L
G
----
I
K
A
-
N
D
T
Q
E
F
N
LS
A
Y
-
F
E
R
A
A
D
F
I
-
D
Q
A
L
A
Q
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
40
SP3
60.58
12%
-15
- C6 -
1JMX
1
?
A:
[364-494]
----------------------------------------------------------
K
V
E
-
E
V
K
V
V
P
A
F
S
I
A
R
I
G
E
---------
N
G
A
S
------
V
P
K
V
-
Q
G
R
F
E
A
E
A
W
G
-----
K
D
A
N
G
Q
P
L
R
I
G
Y
L
P
A
S
W
K
---
V
E
P
F
N
-------
E
R
A
V
E
D
E
D
V
K
F
----
A
G
K
M
-------------
Q
A
D
G
V
F
V
---------
P
G
G
A
G
P
N
P
E
R
K
M
M
T
-
N
-
N
A
-
G
N
L
K
V
I
A
T
L
A
------------------------------------------------------------
D
G
-----------
G
Q
T
G
------
E
G
H
M
I
V
T
--------
V
--
Q
R
W
N
N
--
P
-
P
----------
L
P
-------------------------------------------------------
1
PsiBlast_PDB
59.55
28%
15
- C3 -
1J4X
-
DUS3_HUMAN
A:
[54-114]
----------------------------------------------------------------------------
G
--
I
T
H
V
L
N
A
A
E
G
R
S
F
M
H
V
N
T
N
A
N
--------
F
Y
K
-----
D
--
S
G
I
-
T
Y
L
G
----
I
K
A
-
N
D
T
Q
E
F
N
LS
A
Y
-
F
E
R
A
A
D
F
I
-
D
Q
A
L
A
Q
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
Fugue
59.20
13%
-37
* C4 *
4I66
-
?
A:
[5-207]
------------------
A
F
R
F
G
Q
L
A
------------------------
L
G
D
I
Y
P
Q
A
L
S
R
M
S
R
E
I
D
K
R
T
S
I
------------
E
A
A
R
E
P
A
A
V
T
L
S
S
P
T
---
L
H
E
T
P
F
L
Y
L
-----
A
--
G
D
R
-
E
F
A
I
----
P
P
E
-
P
E
V
E
A
L
R
--
R
H
-
L
T
F
G
G
F
L
L
I
D
S
A
E
G
A
L
G
G
A
F
D
-------------
R
S
V
R
R
L
L
---------
Q
A
V
F
P
A
P
A
P
G
L
E
I
V
-
S
G
E
H
-
V
V
F
K
S
F
Y
L
L
E
----
R
P
L
G
R
L
A
L
----
S
P
V
M
E
-------------------------------------
G
I
L
R
-----------
D
G
R
L
M
V
A
Y
V
Q
N
D
L
G
G
A
F
--------
A
--
R
D
D
F
G
N
F
Q
L
A
----------
C
V
P
D
G
E
R
Q
R
E
L
A
F
R
M
L
V
N
L
V
M
Y
A
L
C--------------------------------
25
Fugue
58.20
17%
-7
- C2 -
4EYT
-
?
A:
[10-106]
------------------------------------------------
K
Q
N
C
L
I
K
I
I
N
I
P
Q
-
G
T
L
K
A
E
V
V
L
A
V
R
H
L
G
--
Y
E
F
Y
C
D
Y
I
D
G
Q
A
M
I
R
F
Q
N
S
D
E
Q
R
L
A
I
Q
K
L
L
N
H
-----
N
--
N
N
K
-
L
Q
I
E
----
I
R
G
-
Q
I
C
D
V
I
S
--
T
I
P
E
D
E
E
K
N
Y
W
N
Y
I
K
F
K
K
N
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
Fugue
57.07
13%
-26
- C5 -
3FPP
-
MACA_ECOLI
A:
[43-308]
------------------
P
G
D
L
Q
Q
S
V
L
A
--
T
G
K
----
L
D
A
L
R
K
V
D
V
G
A
Q
V
S
G
Q
L
K
T
L
S
V
A
I
-
G
D
K
V
K
K
D
Q
L
L
G
V
I
D
P
--
E
Q
A
E
N
Q
I
K
E
V
E
A
T
L
M
E
L
R
A
Q
R
-
Q
Q
A
E
A
E
L
K
L
A
-----
R
--
V
T
Y
-
S
R
Q
Q
----
R
L
A
Q
T
Q
A
V
S
Q
Q
--
D
L
-
D
N
A
A
T
E
M
A
V
K
Q
A
Q
I
G
T
I
D
A
Q
I
-------------
K
R
N
Q
A
S
L
D
T
A
K
T
N
L
D
Y
T
R
I
V
A
P
M
A
G
E
V
T
Q
I
-
T
T
L
Q
G
Q
T
V
I
A
A
Q
Q
A
P
N
I
L
T
L
A
D
M
S
A
M
L
----
V
K
A
-
Q
V
S
EADVIHLKPG
Q
K
A
W
F
T
V
LGDQLT
R
Y
E
G
Q
I
K
D
V
L
P
T
P
E
K
V
-----------
N
D
A
I
------
F
Y
Y
A
R
F
E
--------
V
--
P
N
P
N
G
L
L
R
-
L
DM
T
A
Q
V
H
I
Q
L
T
D
V
K
N
V
L
T
-------------------------------------------------
41
SP3
48.05
8%
-31
* C6 *
2HFT
-
?
?:
[1-106]
-----------------------------------------------------
S
G
T
T
N
T
V
A
-
A
Y
N
L
T
W
K
S
T
N
F
K
T
I
---
L
E
W
E
-------------
P
K
P
V
-
N
Q
V
Y
T
V
Q
I
S
T
-----
K
--
S
G
D
-
W
K
S
K
----
C
F
Y
-
T
T
D
T
E
C
D
-----------------
L
T
D
E
I
V
K
D
V
-------------
K
Q
T
Y
L
A
R
---------
V
F
S
Y
P
A
G
N
V
E
S
T
E
----------
P
L
Y
E
N
S
P
E---
F
T
P
Y
L
E
T
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
46.80
38%
35
- C8 -
3M2R
-
MCRG_METTM
C:
[195-228]
--------------------------------------------------
D
E
P
V
D
L
G
E
P
L
D
-
E
E
T
L
M
E
K
T
T
I
Y
R
V
D
G
--
E
A
Y
R
D
D
V
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
46.78
38%
29
* C8 *
3M2U
-
MCRG_METTM
C:
[195-228]
--------------------------------------------------
D
E
P
V
D
L
G
E
P
L
D
-
E
E
T
L
M
E
K
T
T
I
Y
R
V
D
G
--
E
A
Y
R
D
D
V
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
46.51
38%
39
- C8 -
3M32
-
MCRG_METTM
C:
[195-228]
--------------------------------------------------
D
E
P
V
D
L
G
E
P
L
D
-
E
E
T
L
M
E
K
T
T
I
Y
R
V
D
G
--
E
A
Y
R
D
D
V
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
46.34
38%
36
- C8 -
1HBM
-
MCRG_METTM
C:
[195-228]
--------------------------------------------------
D
E
P
V
D
L
G
E
P
L
D
-
E
E
T
L
M
E
K
T
T
I
Y
R
V
D
G
--
E
A
Y
R
D
D
V
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
46.20
38%
40
- C8 -
1HBN
-
MCRG_METTM
C:
[195-228]
--------------------------------------------------
D
E
P
V
D
L
G
E
P
L
D
-
E
E
T
L
M
E
K
T
T
I
Y
R
V
D
G
--
E
A
Y
R
D
D
V
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
46.14
38%
40
- C8 -
3M30
-
MCRG_METTM
C:
[195-228]
--------------------------------------------------
D
E
P
V
D
L
G
E
P
L
D
-
E
E
T
L
M
E
K
T
T
I
Y
R
V
D
G
--
E
A
Y
R
D
D
V
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
45.98
38%
38
- C8 -
3M1V
-
MCRG_METTM
C:
[195-228]
--------------------------------------------------
D
E
P
V
D
L
G
E
P
L
D
-
E
E
T
L
M
E
K
T
T
I
Y
R
V
D
G
--
E
A
Y
R
D
D
V
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
45.33
38%
41
- C8 -
1HBO
-
MCRG_METTM
C:
[195-228]
--------------------------------------------------
D
E
P
V
D
L
G
E
P
L
D
-
E
E
T
L
M
E
K
T
T
I
Y
R
V
D
G
--
E
A
Y
R
D
D
V
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
User Run . : Multi Template Modeling Result:
(2 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200..
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MKR
L
L
L
I
T
L
L
I
G
Y
I
Y
P
CVAQDKPIRTEESLE
G
T
V
I
Y
K
K
T
T
T
F
E
VD
G
Y
T
Y
Q
C
DVDDG
S
Q
F
V
T
L
YNKENKL
T
Y
E
K
I
V
Y
KDTG
K
T
Y
IGSWSS
N
V
I
E
Y
D
R
F
M
S
Q
Q
A
D
F
I
V
D
Q
A
F
T
K
A
M
A
D
EIGK
T
E
L
M
I
T
M
L
LSPNTG
E
V
M
E
V
N
F
N
F
F
T
FEPYAKV
P
L
H
V
Y
R
E
I
E
V
K
L
K
EQIH
F
K
PIEEGKQL
N
Y
I
M
L
A
W
MQKPQGKLPPLPPPGSLM
62
60.51
100%
-0
- C- -
M062
-
A:
[21-54]
--------------------
D
K
P
I
R
T
E
E
S
L
E
G
T
V
I
Y
K
K
T
T
T
F
E
V
D
G
Y
T
Y
Q
C
D
V
D
------------------------------------------------------------------------------------------------------------------------------------------------------
55
55.71
100%
30
- C- -
M055
-
A:
[21-54]
--------------------
D
K
P
I
R
T
E
E
S
L
E
G
T
V
I
Y
K
K
T
T
T
F
E
V
D
G
Y
T
Y
Q
C
D
V
D
------------------------------------------------------------------------------------------------------------------------------------------------------